Ingredient glossary

Madecassoside

What Madecassoside does for your skin, who it suits, and what to watch for.

INCI: Madecassoside · Also: Centella Triterpene, Cica Triterpene

Scent, not skincare

In short: Madecassoside delivers anti inflammatory and repair, suits dry and sensitive skin best, and the evidence behind it is moderate.

What it does
Anti inflammatory, repair
Best for
Dry, Sensitive skin
Evidence
Moderate
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The molecule

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Chemical structure of Madecassoside (Madecassoside)

The Glow take

The first thing I would drop if skin turns reactive.

Your skin gains nothing from Madecassoside beyond the scent, and fragrance is one of the most common triggers for irritation. If your skin is calm, it is usually fine.

— Maya

What it does

  • anti inflammatory
  • repair
  • anti aging
  • barrier support

moderate evidenceClinical trials combining five percent vitamin C with zero point one percent madecassoside show long term improvements in wrinkles hydration elasticity and elastic fiber structure in sun damaged skin.

On a label: usually effective at 0.1-0.3%.

Who it's for, and who should skip it

Tends to suit

  • sensitive
  • dry
  • compromised barrier
  • photoaged

Approach with care

No specific group flagged to avoid it.

  • Clogs poresLow
  • Irritation riskLow

How it fits each skin type

  • DrySuits
  • CombinationNeutral
  • OilyNeutral
  • SensitiveSuits

Often chosen for compromised barrier, photoaged.

Where it fits in your routine

WhenMorning or evening
Where in the orderAfter cleansing, before your moisturizer

Plays well with

Madecassoside, answered

Is Madecassoside safe during pregnancy?

Yes. Madecassoside is considered safe to use during pregnancy and breastfeeding. As with anything, if you are unsure it is worth a quick word with your doctor or midwife.

Who should avoid Madecassoside?

No specific group is flagged to avoid Madecassoside. It is well tolerated by most skin. Still, introduce anything new one product at a time.

What concentration of Madecassoside actually works?

Madecassoside tends to do its job in the 0.1 to 0.3% range. Much lower and it is likely underdosed.

This, for every label you own

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Sources & how we reviewed this

Last reviewed July 2026. Educational information about a cosmetic ingredient, not medical advice.