Ingredient glossary

Isopropyl Palmitate

What Isopropyl Palmitate does for your skin, who it suits, and what to watch for.

INCI: Isopropyl Palmitate

Decent support

In short: Isopropyl Palmitate delivers softening and slip, suits most skin types, and the evidence behind it is moderate. One thing to know: may clog acne-prone skin.

What it does
Softening, slip
Best for
Most skin types
Watch out
May clog acne-prone skin
Evidence
Moderate
Does it clash with what you use? Check it →

The molecule

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Chemical structure of Isopropyl Palmitate (Isopropyl Palmitate)

The Glow take

A comfort ingredient, and none the worse for it.

Isopropyl Palmitate is here for feel and moisture, softening the skin and slowing water loss. More comfort than correction.

— Maya

What it does

  • softening
  • slip

moderate evidenceFrequently listed in comedogenicity references and user reports as problematic for breakout-prone and fungal-acne-prone skin.

On a label: usually effective at 1-10%.

Who it's for, and who should skip it

Tends to suit

  • dry
  • normal

Approach with care

  • acne prone
  • fungal acne prone
  • Irritation riskLow

How it fits each skin type

  • DrySuits
  • CombinationSuits
  • OilySuits
  • SensitiveSuits

Take extra care if any of these apply to you: acne prone, fungal acne prone.

Where it fits in your routine

WhenMorning and evening
Where in the orderAfter your actives, to seal everything in

Plays well with

  • humectants
  • occlusives

Isopropyl Palmitate, answered

Is Isopropyl Palmitate safe during pregnancy?

Yes. Isopropyl Palmitate is considered safe to use during pregnancy and breastfeeding. As with anything, if you are unsure it is worth a quick word with your doctor or midwife.

Who should avoid Isopropyl Palmitate?

Approach Isopropyl Palmitate with care if any of these apply to you: acne prone and fungal acne prone. It carries a high risk of clogging pores, so acne-prone skin should go carefully.

What concentration of Isopropyl Palmitate actually works?

Isopropyl Palmitate tends to do its job in the 1 to 10% range. Much lower and it is likely underdosed.

Does it clog pores?

4/5
High

A light ester that rates fairly high for clogging pores in isolation.

  • This rating comes from old lab tests on the isolated ingredient, not the finished product.
  • The full formula, how much is used, and your own skin all matter more than one number.
  • If you are acne-prone it is worth noticing, not a reason to avoid it on sight.

Commonly confused with

  • Isopropyl MyristateTwo near-identical ester emollients. Myristate is the lighter one and rates a little higher for clogging pores.

This, for every label you own

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Sources & how we reviewed this

Last reviewed July 2026. Educational information about a cosmetic ingredient, not medical advice.