Ingredient glossary

Dipotassium Glycyrrhizate

What Dipotassium Glycyrrhizate does for your skin, who it suits, and what to watch for.

INCI: Dipotassium Glycyrrhizate · Also: Dipotassium Glycyrrhizin, Licorice Root Derivative

Solid and proven

In short: Dipotassium Glycyrrhizate delivers soothing and anti inflammatory, suits sensitive skin best, and the evidence behind it is moderate.

What it does
Soothing, anti inflammatory
Best for
Sensitive skin
Evidence
Moderate
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The molecule

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Chemical structure of Dipotassium Glycyrrhizate (Dipotassium Glycyrrhizate)

The Glow take

Genuinely worth a spot in your routine.

When your goal is repairing a stressed moisture barrier, Dipotassium Glycyrrhizate pulls genuine weight, with a solid amount of evidence behind it. It tends to suit sensitive skin best.

— Maya

What it does

  • soothing
  • anti inflammatory
  • barrier support
  • anti redness

moderate evidenceRandomized parallel group studies of emollients containing dipotassium glycyrrhizin show significant reductions in SCORAD pruritus scores and flare frequency in adults with atopic dermatitis without notable adverse events.

On a label: usually effective at 0.1-0.5%.

Who it's for, and who should skip it

Tends to suit

  • sensitive
  • very sensitive
  • atopic
  • acne prone
  • compromised barrier

Approach with care

  • rare licorice allergy
  • Clogs poresLow
  • Irritation riskLow

How it fits each skin type

  • DryNeutral
  • CombinationNeutral
  • OilyNeutral
  • SensitiveSuits

Often chosen for atopic, acne prone, compromised barrier. Take extra care if any of these apply to you: rare licorice allergy.

Where it fits in your routine

WhenMorning or evening
Where in the orderAfter cleansing, before your moisturizer

Plays well with

Dipotassium Glycyrrhizate, answered

Is Dipotassium Glycyrrhizate safe during pregnancy?

Yes. Dipotassium Glycyrrhizate is considered safe to use during pregnancy and breastfeeding. As with anything, if you are unsure it is worth a quick word with your doctor or midwife.

Who should avoid Dipotassium Glycyrrhizate?

Approach Dipotassium Glycyrrhizate with care if any of these apply to you: rare licorice allergy.

What concentration of Dipotassium Glycyrrhizate actually works?

Dipotassium Glycyrrhizate tends to do its job in the 0.1 to 0.5% range. Much lower and it is likely underdosed.

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Sources & how we reviewed this

Last reviewed July 2026. Educational information about a cosmetic ingredient, not medical advice.