Ingredient pairing

Can you mix GHK-Cu and Gluconolactone?

Use with careUse these with care.

GHK-CuGluconolactone

Low-pH acids and pure vitamin C can destabilize copper peptides, so side by side they may simply do less.

Do this: Keep the copper peptides in a separate routine, morning or evening.

Routine: Best kept in separate routines, morning and evening.

GHK-CuSolid and proven
Efficacy7
Anti-aging7
Barrier4
GluconolactoneSolid and proven
Efficacy8
Hydration7
Barrier6
Ask your doctor in pregnancy

Which one goes first?

Best kept apart

Rather than layering them, keep GHK-Cu and Gluconolactone in separate routines or on separate days.

How to introduce GHK-Cu and Gluconolactone

  1. Patch test each one first: a coin-sized amount on your inner forearm for two or three days, watching for redness or stinging.
  2. Keep them on separate days rather than together, so they are not both working on your skin at once.
  3. Start the exfoliating acid at once or twice a week and increase gradually, giving your skin time to settle between steps.
  4. If skin turns tight, flaky, red or starts to sting, drop back a step and let your barrier recover for a few days before pushing on again.

There is room for both here, as long as you build up gently and let your skin set the pace.

For your skin type Both sit low on the irritation scale, so most skin types get on with them, though sensitive skin should still add one at a time.

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GHK-Cu and Gluconolactone, answered

Can you mix GHK-Cu and Gluconolactone?

Use these with care. Low-pH acids and pure vitamin C can destabilize copper peptides, so side by side they may simply do less. Keep the copper peptides in a separate routine, morning or evening.

Should you use GHK-Cu and Gluconolactone in the morning or at night?

Keep them in separate routines or on separate days rather than at the same time.

How should you introduce GHK-Cu and Gluconolactone?

Patch test each one first: a coin-sized amount on your inner forearm for two or three days, watching for redness or stinging. Keep them on separate days rather than together, so they are not both working on your skin at once. Start the exfoliating acid at once or twice a week and increase gradually, giving your skin time to settle between steps. If skin turns tight, flaky, red or starts to sting, drop back a step and let your barrier recover for a few days before pushing on again. There is room for both here, as long as you build up gently and let your skin set the pace.

What else should you not mix with GHK-Cu?

Nothing else clashes badly with GHK-Cu. It fits into most routines, though it is always wise to introduce one new product at a time.

Sources

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General guidance, not medical advice. When in doubt, introduce one product at a time.